VerifiedRx

2021-07

Episodes

Wednesday Jul 28, 2021

Vizient publishes the Pharmacy Market Outlook twice a year to project drug prices and key market trends for the next 18-months.  Pharmacists use this information to budget and project their supply needs.  Carina Dolan, Senior Director for Clinical Oncology and Pharmaceutical Outcomes at Vizient shares details revealed in the summer 2021 edition of the Pharmacy Market Outlook. 
 
Guest speaker:
Carina Dolan, PharmD, MS, BCOP
Senior Director for Clinical Oncology and Pharmaceutical Outcomes
Pharmacy Solutions
Vizient
 
Moderator:
Gretchen Brummel, PharmD, BCPS
Pharmacy Executive Director
Vizient Center for Pharmacy Practice Excellence
 
Show Notes:
[1:16] The Pharmacy Market Outlook is a bi-annual report that projects drug prices for 18 months, and reviews the trends of the various market segments.
[2:08] How the report is calculated
[2:45] Purchases made through 340B program and direct or outsourced purchases made by hospitals are not included in the Pharmacy Market Outlook.
[3:02] Prediction of the drug price inflation rate for January – December 2022
[3:38] How the Vizient Pharmacy Market Outlook compares to other drug forecasting reports.
[4:01] The estimate drug price inflation rate for the upcoming calendar year is anticipated to have a moderate price increase.
[4:30] The largest contributor to drug price increases is at Adalimumab and will remain that way until 2023.
[4:49] The Vizient Drug Price Forecast Report in the Vizient Savings Actualyzer can help you with your budget. It pulls your wholesale purchase data and self-populates the projections of the report. It has the capability to use your institutes direct purchases.
[5:25] Closer Look features the different segments of the market including acute care, non-acute care, specialty pharmaceuticals and pediatrics.
[5:34] The report has a projected timeline graphic that shows investigational medications likely to be approved and other events likely to happen during the 18-month timeframe.  
[6:40] The current, high-priority advocacy topics include 340B pricing for contract pharmacies, white-bagging for provider-administered medications, the unapproved drugs initiative (UDI) and changes to the FDA enforcement of Action.
[7:25] Accelerated Approval Pathways
[7:25] Example: Aducanumab, brand name: Adulhelm, for the treatment of Alzheimer’s disease  
[9:10] New topic highlighted is therapeutic class (i.e. diabetes and related medications)
[9:52] Vizient members can access the report online through the website at Vizientinc.com/pharmacysolutions.com, then go to My Dashboard to access the Vizient Pharmacy Market Outlook report.
[10:06] Non-Vizient members can access a public version on the VizientInc.com
[10:15] The drug budget report may be accessed through the Vizient Savings Actualyzer Pharmacy.
[10:20] If you have issues accessing the report or other questions, please email PharmacyQuestions@Vizientinc.com
 
Links | Resources:
Vizient Pharmacy Market Outlook - member version Click here
Vizient Pharmacy Market Outlook highlights - public version Click here
 
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Tuesday Jul 13, 2021

Ischemic stroke is the leading cause of morbidity and mortality in the United States, taking the lives of 140,000 people each year.  Historically, the thrombolytic alteplase has been the mainstay of drug therapy, but now the FDA is looking at tenecteplase as a treatment option for ischemic strokes.
 
Guest speaker:
Philippe Mentler, PharmD, BCPS
Consulting Director, Pharmacy
Vizient
 
Moderator:
Gretchen Brummel, PharmD, BCPS
Pharmacy Executive Director
Vizient Center for Pharmacy Practice Excellence
 
Show Notes:
[01:03] The treatment of ischemic strokes prior to alteplase
[01:46] Controversies in the original clinical trials of alteplase, including the 1995 NINDS trial
[02:45] The advances in imaging and patient care since the initial trials
[03:58] The difficulties of administering alteplase – including estimating a patient’s weight
[04:50] The consequences of under-dosing
[06:00] Tenecteplase: A potential alternative to alteplase
[06:47] Variances of tenecteplase and alteplase in clinical trials
[07:37] Determining the choice of one drug over the other
[08:41] Clinical outcomes of tenecteplase vs. alteplase
[10:37] Determining when to convert from alteplase to tenecteplase
[12:17] Anticipating tenecteplase will eventually get FDA approval
 
Links | Resources:
American Heart Association: Stroke, AHA/ASA Guideline, December 2019 Click here
AHA Journals, Tenecteplase Thrombolysis for Acute Ischemic Stroke: Click here
 
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